List of Equipment used in SFD (Solid Dosage Form) Pharma Manufacturing Process

List of equipment used in the solid dosage form (SDF) manufacturing process, along with a brief definition and explanation of their purpose:

1. Granulation Equipment: Used to mix and granulate the active pharmaceutical ingredient (API), excipients and other materials. This process enhances the flowability of the powders and facilitates uniform mixing.

2. Milling Equipment: Used to grind and mill raw materials into a fine powder, which is typically used in dry granulation or compression processes. Milling ensures that the particles are uniform in size, which leads to consistent, high-quality products.

3. Blending Equipment: Used to blend granules or powders together to ensure uniformity in the final product. This process is critical to ensuring that each tablet or capsule contains the same amount of active ingredient.

4. Compaction Equipment: Used to compress the granules or powders into a compact mass before they are pressed into tablets. The compactors use a combination of force and pressure to create dense, uniform masses from the powders and granules.

5. Tablet Presses: Used to compress granules or powders into tablets of various shapes and sizes. The tablet press uses punches and dies to shape the compacted material into tablets that meet specific size, weight, and thickness requirements.

6. Coating Equipment: Used to apply a coating to tablets or capsules for aesthetic purposes or to control the release of the drug into the body. Coating can also mask unpleasant tastes or odors and protect the tablet from moisture and light.

7. Capsule Filling Machines: Used to fill capsules with granules or powders, often used when the API cannot be compressed into a tablet. Capsule filling machines can produce capsules of different sizes and shapes, depending on the specific requirements of the product.

8. Packaging Equipment: Used to package finished products into their final containers, such as bottles or blister packs. This equipment can also seal the packaging to protect the tablets from moisture and other external factors.

9. Labeling Equipment: Used to apply labels to packaging materials, ensuring that the products meet regulatory requirements and contain all necessary information. Labels may include information about the drug product, manufacturer's name, dosage form, strength, batch number, and expiration date.

Each piece of equipment plays a critical role in the manufacturing process, from raw material processing to final packaging and labeling. Proper use and maintenance of each piece of equipment is essential to ensure the quality, safety, and consistency of the final product.